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Type 1 and type 2 responses to Leishmania major

✍ Scribed by Kathleen A. Rogers; Gregory K. DeKrey; M.Lamine Mbow; R.Dean Gillespie; Claudia I. Brodskyn; Richard G. Titus

Book ID
117517309
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
232 KB
Volume
209
Category
Article
ISSN
0378-1097

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We recently reported that the infection of macrophages with Leishmania major led to the release of type 1 interferons (IFN- Β§ / g ). Moreover, at day 1 of infection of mice with L. major, IFN- Β§ / g was required for the expression of type 2 (inducible) NO synthase (NOS2 or iNOS) which, however, was