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TxA2 platelet receptors after Picotamide in vivo administration

โœ Scribed by Modesti, P.A.; Colella, A.; Cecioni, I.; Martini, F.; Abbate, R.; Neri Serneri, G.G.

Book ID
123429650
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
148 KB
Volume
4
Category
Article
ISSN
0268-9499

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โœ M. Berrettini; M. Cunto; P. Parise; S. Grasselli; G. G. Nenci ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 599 KB

Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas