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Two-year oral chronic toxicity and carcinogenicity study in rats of diets fumigated with methyl bromide

โœ Scribed by K. Mitsumori; K. Maita; T. Kosaka; T. Miyaoka; Y. Shirasu

Book ID
119159964
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
811 KB
Volume
28
Category
Article
ISSN
0278-6915

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Five-hundred and sixty Sprague-Dawley rats were randomized into one control and three treatment groups (70 of each sex per group). Animals were treated by daily gavage with 0.0, 0.05, 0.5 and 2.5 mg kg-' acrolein in water (10 ml kg-I). These dosing levels were selected as a result of a 6-week range-