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Two variants of the TLS-CHOP fusion transcript in myxoid liposarcomas with the 12;16 translocation

✍ Scribed by Ioannis Panagopoulos; Pierre Åman; David Ron; Mattias Höglund; Nils Mandahl; Felix Mitelman


Book ID
113253504
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
91 KB
Volume
77
Category
Article
ISSN
0165-4608

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📜 SIMILAR VOLUMES


Additional evidence of a variant translo
✍ Dal Cin, Paola; Sciot, Raf; Panagopoulos, Ioannis; Åman, Pierre; Samson, Ignace; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB

It is well established that the majority of myxoid/round cell liposarcomas (LPS) are characterized by a reciprocal translocation t(12;16)(q13;p11) which at the molecular level results infusion of the CHOP and FUS/TLS genes. It is assumed that functional characterization of these genes may provide in

Rearrangement of the transcription facto
✍ Dr. Pierre Åman; David Ron; Nils Mandahl; Thoas Fioretos; Sverre Heim; Kristina 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 809 KB

Most myxoid liposarcomas (MLS) are characterized cytogenetically by a t( 12; I6)(q I3:p I I). It is reasonable t o assume that this translocation corresponds t o the consistent rearrangement of one o r t w o genes in 12q I 3 and/or I6p I I, and that the loci thus affected are important in the normal