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Two theonellapeptolide congeners from marine sponge Theonella sp.

โœ Scribed by Masashi Tsuda; Kazutaka Shimbo; Takaaki Kubota; Yuzuru Mikami; Jun'ichi Kobayashi

Book ID
104209554
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
512 KB
Volume
55
Category
Article
ISSN
0040-4020

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โœฆ Synopsis

Two new theonellapeptolide-related cyclic depsipeptides (1 and 2) have been isolated from an Okinawan marine sponge Theonella sp. and the structures were elucidated on the basis of the 2D NMR data, PSD analysis of MALDI-TOFMS, and chemical means. Compound 1 was a theonellapeptolide congener possessing a methylsulfmylacetyl group at the N-terminus, while 2 was another theonellapeptolide congener having an acetyl group at the N-terminus. Compounds I and 2 exhibited antimicrobial activity.

๐Ÿ“œ SIMILAR VOLUMES

Amphipathic structure of Theonellapeptol
Amphipathic structure of Theonellapeptolide-Id, a hydrophobic tridecapeptide lactone from the Okinawa marine sponge Theonella swinhoei
โœ Mitsunobu Doi; Toshimasa Ishida; Motomasa Kobayashi; Yoshio Katsuya; Yoshihiro M ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 215 KB ๐Ÿ‘ 1 views

Theonellapeptolide-Id (TNLP), a cyclic tridecapeptide lactone, was crystallized from dimethylformamide-water solution. In the asymmetric unit, two peptide molecules were combined with solvent molecules, and the total molecular weight was over 3000 Dalton. The crystal structure including solvent mole