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Two-step ligand binding and cooperativity. A model to describe the cooperative binding of myosin subfragment 1 to regulated actin

✍ Scribed by Geeves, M.A.; Halsall, D.J.

Book ID: 118518873
Publisher: Biophysical Society
Year: 1987
Tongue: English
Weight: 640 KB
Volume: 52
Category: Article
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(87)83208-3

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## Abstract The theoretical study of the cooperative binding of a small ligand to a linear homopolymer is extended to systems in which two different complexes can form. The binding isotherms are derived under the assumption that the cooperative interactions exist only between molecules belonging to