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Two-stage glycerol feeding for enhancement of recombinant hG-CSF production in a fed-batch culture ofPichia pastoris

✍ Scribed by A. Bahrami; S. A. Shojaosadati; R. Khalilzadeh; E. Vasheghani Farahani

Book ID: 106364159
Publisher: Springer Netherlands
Year: 2008
Tongue: English
Weight: 246 KB
Volume: 30
Category: Article
ISSN: 0141-5492
DOI: 10.1007/s10529-008-9650-4

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## Abstract **BACKGROUND:** A simple and efficient model for enhancing production of recombinant proteins is essential for cost effective development of processes at industrial scale. A hybrid neural network (HNN) model is proposed combining an unstructured model and neural network to predict the f