Two siblings with nerve conduction abnormalities indicating an acquired type of demyelinating neuropathy
✍ Scribed by Akira Inaba; Takanori Yokota; Toshiaki Shiojiri; Masahito Yamada
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 180 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0148-639X
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✦ Synopsis
Although an acquired demyelinating neuropathy perineurial edema nor inflammatory cell infiltration was seen. The thinly myelinated fibers made up a may be associated with a genetic factor such as the human leukocyte antigen (HLA) phenotype, 1,14 its quarter of the myelinated fibers.
Quantitative Southern blot analysis 4 revealed no familial occurrence is rare. 5,7 We here report 2 siblings with demyelinating neuropathy showing nerve deletion of PMP-22.
Nerve conduction studies revealed motor con-conduction abnormalities considered characteristic of acquired type of lesions.
duction velocity and distal/proximal amplitude of 20 m/s and 10.2 mV/3.9 mV for the right median CASE