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Two proteins with the same structure respond very differently to mutation: the role of plasticity in protein stability

✍ Scribed by Ernesto Cota; Stefan J. Hamill; Susan B. Fowler; Jane Clarke


Book ID
115630494
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
493 KB
Volume
302
Category
Article
ISSN
0022-2836

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Earlier studies involving water-mediated transformations in lysozyme and ribonuclease A have shown that the overall movements in the protein molecule consequent to the reduction in the amount of surrounding water are similar to those that occur during enzyme action, thus highlighting the relationshi