Two-pool model analysis of data in hemodialysis by means of programmable pocket calculator TI 59
✍ Scribed by R. Guthke; K. Günther; G. Stein; W.A. Knorre
- Publisher
- Elsevier Science
- Year
- 1985
- Weight
- 369 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0010-468X
No coin nor oath required. For personal study only.
✦ Synopsis
Four parameters of a two-pool model are evaluated by an iterative method using the explicit solutions of the linear differential equations. For this it was presumed that the residual renal clearance is sufficiently small. Five data pairs of measured plasma concentrations c i for the time points t i (i = 0 to 4), as well as the dialyzer and residual renal clearances (K D and KR), must be given and put in the calculator. A sample run is shown for urea kinetics. The parameter estimation takes about 10 min. The program is suitable to assist in the individualization of dialysis therapy.
Hemodialysis Two-pool model Parameter estimation