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Two polymorphisms in the apo A-IV gene and familial combined hyperlipidemia

✍ Scribed by Martine Groenendijk; Tjerk W.A. De Bruin; Geesje M. Dallinga-Thie

Book ID: 119435248
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 106 KB
Volume: 158
Category: Article
ISSN: 0021-9150
DOI: 10.1016/s0021-9150(01)00460-9

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## Abstract Human apolipoprotein A‐IV (APO A‐IV) exhibits a common protein polymorphism detectable by isoelectric focusing (IEF) due to a single base substitution at codon 360 which replaces the frequently occurring glutamine residue (allele 1) with histidine (allele 2). Recently, sequence analysis