Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines
✍ Scribed by Christophe J. Bergeron, Hirak S. Basu…
- Book ID
- 120776400
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 652 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0344-5704
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We studied the effects of the spermine analogue N',N14-bis-(ethyl)-homospermine (BE-4-4-4) on growth, survival and polyamine levels in cultured U-251 MG and SF-188 human brain tumor cells. After 48 hr of treatment at concentrations of I )LM or higher, BE-4-4-4 accumulated in cells with a concomitant
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