Two-Phase Aqueous Extraction of Copper(II) and Its Application to Speciation Analysis of Serum Copper

✍ Scribed by Zhi-Hua Wang; Yi Zeng; Hui-Min Ma; Shu-Chuan Liang

• Publisher: Elsevier Science
• Year: 1998
• Tongue: English
• Weight: 91 KB
• Volume: 60
• Category: Article
• ISSN: 0026-265X
• DOI: 10.1006/mchj.1998.1649

✦ Synopsis

The extraction of copper(II) with the two-phase aqueous system isopropyl alcohol-ammonium sulfate-ammonium thiocyanate [i-PrOH-(NH 4 ) 2 SO 4 -NH 4 SCN] was studied and the related experimental conditions were optimized. The results show that Cu(II) can be quantitatively extracted under the selected conditions: 4 ml of i-PrOH, 1 ml of 6 mol/liter sulfuric acid (H 2 SO 4 ), 1 ml of 2.5 mol/liter NH 4 SCN, and 5 g of (NH 4 ) 2 SO 4 (V total ϭ 15 ml). Application of the proposed method to speciation analysis of serum copper was also investigated and satisfactory results were obtained.