Infusion of insulin impairs human adipoc
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L. Mandarino; B. Baker; R. Rizza; J. Genest; J. Gerich
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Article
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1984
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Springer
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English
β 693 KB
To determine whether hyperinsulinaemia can cause insulin resistance in man and, if so, whether this occurs at a receptor or post-receptor site, nine normal volunteers were infused with insulin for 6 h at a rate (2 mU X kg-1 X min-1) which resulted in steady-state plasma insulin concentrations of 140