Two optimization techniques as used in a general four compartment first-order system
✍ Scribed by Y. Cherruault; V.B. Sarin
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 523 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0895-7177
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✦ Synopsis
Life is a continuously changing phenomenon, and ,the capacity to observe time-dependent processea by nondestructive means (for example, by tracer techniques) provides functional information which cannot be otherwise obtained. The present study deals with the identification of exchange parameters for a general four compartment model in which the tracer in every compartment can exchange with every other compartment. The method of solution is based on two optimization techniques, namely: the Alienor technique and the Gabriel technique. These techniques reduce different unknowns involved in the problem to a single variable f7, with the help of Archimedes' spiral, thus leading to the global minimum of a functional of single variable 0. Results are compared with those obtained by generalized least squares method in terms of accuracy and computational time.