Two novel α-tocopheroids from the aerial roots of Ficus microcarpa

✍ Scribed by Yi-Ming Chiang; Yueh-Hsiung Kuo

• Book ID: 104253801
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 218 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01116-x

✦ Synopsis

Two novel a-tocopheroids, namely a-tocospiros A (1) and B (2), together with a-tocopherol (3) were isolated from the aerial roots of Ficus microcarpa. Their structures were elucidated by spectral methods. Under basic conditions, compounds 1 and 2 were obtained from a-tocoquinon-2,3-oxide (6a and 6b) via a highly stereoselective nucleophilic addition reaction. Reaction and biotransformation mechanisms of 1 and 2 are proposed.