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Two novel mutations in X-linked agammaglobulinemia

✍ Scribed by I.V. Kondratenko; L. Gomez; S.M. Tverskaya; I.B. Resnick


Book ID
117326069
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
249 KB
Volume
35
Category
Article
ISSN
0161-5890

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For the Immunogenetics Special Issue X-linked agammaglobulinemia (XLA) is a hereditary immunodeficiency caused by mutations in the gene encoding Bruton tyrosine kinase (BTK). XLA patients have a decreased number of mature B cells and a lack of all immunoglobulin isotypes, resulting in susceptibility

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