Two novel mutations in a cystic fibrosis patient of Chinese origin
β Scribed by John A. Wagner; Athina Vassilakis; Kevin Yee; Mei Li; Gregory Hurlock; Mauri E. Krouse; Richard B. Moss; J. J. Wine
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 175 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0340-6717
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π SIMILAR VOLUMES
Cyprus is an island in the eastern Mediterranean basin inhabited by people of Caucasian extraction, mostly Greek-Cypriots. The most common inherited disease among Caucasians is cystic fibrosis (CF). Although no careful scientific study had ever been done the impression was that CF was extremely rare
We carried out molecular analysis of 80 chromosomes from 40 unrelated Mexican patients with a diagnosis of cystic fibrosis. The study was performed in two PCR steps: a preliminary one to identify mutation β¬F508, the most frequent cause of cystic fibrosis worldwide, and the second a reverse dot-blot