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Two novel ADAMTS13 gene mutations in thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome (TTP/HUS)

✍ Scribed by Licht, Christoph; Stapenhorst, Ludwig; Simon, Thorsten; Budde, Ulrich; Schneppenheim, Reinhard; Hoppe, Bernd

Book ID: 109066569
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 82 KB
Volume: 66
Category: Article
ISSN: 0085-2538
DOI: 10.1111/j.1523-1755.2004.00841.x

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We present a case of a patient who developed all manifestations of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) acutely following treatment of cutaneous T-cell lymphoma (CTCL, Sezary syndrome) with deoxycoformycin (pentostatin). Symptoms and signs included severe thrombocy