Folding of RNase T1 is decelerated by a
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Thomas Kiefhaber; Hans-Peter Grunert; Ulrich Hahn; Franz X. Schmid
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Article
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1992
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John Wiley and Sons
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English
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## Abstract The replacement of tryptophan 59 of ribonuclease T1 by a tyrosine residue does not change the stability of the protein. However, it leads to a strong acceleration of a major, prolineβlimited reaction that is unusually slow in the refolding of the wildβtype protein. The distribution of f