Two New Sesquiterpene Polyol Esters from Celastrus angulatus

✍ Scribed by Shao-Peng Wei; Wen-Jun Wu; Zhi-Qin Ji; Ji-Wen Zhang; Yong-Ze Guo; Jian Xue

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: German
• Weight: 180 KB
• Volume: 93
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200900473

✦ Synopsis

Abstract

Two novel sesquiterpene polyol esters with a dihydro‐β‐agarofuran (=(3__R__,5a__S__,9__R__,9a__S__)‐octahydro‐2,2,5a,9‐tetramethyl‐2__H__‐3,9a‐methano‐1‐benzoxepin) skeleton, (1__α__,2__α__,4__β__,8__α__,9__α__)‐1,2,8,12‐tetrakis(acetyloxy)‐9‐(furoyloxy)‐4‐hydroxydihydro‐β‐agarofuran (1) and (1__α__,2__α__,6__β__,8__α__,9__α__)‐1,2,6,8,12‐pentakis(acetyloxy)‐9‐(benzoyloxy)dihydro‐β‐agarofuran (2), and the three known compounds (1__α__,2__α__,4__β__,6__β__,8__α__,9__β__)‐1,2,6‐tris(acetyloxy)‐9‐(benzoyloxy)‐4‐hydroxy‐8,12‐bis(isobutyryloxy)dihydro‐β‐agarofuran (3), (1__α__, 2__α__,4__β__,6__β__,8__α__,9__β__)‐1,2,6,8‐tetrakis(acetyloxy)‐9‐(furoyloxy)‐4‐hydroxy‐12‐isobutyryloxy)dihydro‐β‐agarofuran (4), and (1__α__,2__α__,4__β__,6__β__,8__α__,9__β__)‐1,2,6‐tris(acetyloxy)‐9‐(benzoyloxy)‐4‐hydroxy‐8‐(isobutyryloxy)‐12‐[(2‐methylbutanoyl)oxy]dihydro‐β‐agarofuran (5) were isolated from the root bark of Celastrus angulatus. Their chemical structures were elucidated by analyses of their MS and NMR data.