Two new procedures for the introduction of benzyl-type protecting groups for thiols
β Scribed by Lutz S. Richter; James C. Marsters Jr.; Thomas R. Gadek
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 280 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The benzylation of aliphatic alcohols with various benzylic alcohols has been achieved in the presence of BiBr 3 under mild conditions. 2-Phenylpropan-2-ol proved to be the most efficient and can be considered as a novel protecting group.
Solutions of (4j in organic solvents display an intensive blue fluorescence and in aqueous mineral acids a blue-green fluorescence. In the N M R spectrum (CDC13) a singlet occurs at T = 0.87, which is ascribed to the protons H-1 and H-3 (the neighboring protons to the ring nitrogen); the