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Two New Metabolites, Epoxydine A and B, from Phoma sp.

✍ Scribed by Song Qin; Hidayat Hussain; Barbara Schulz; Siegfried Draeger; Karsten Krohn


Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
195 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

The new compounds, epoxydines A and B (1 and 2, resp.), along with the known and related metabolites, 3–6, were isolated from the fungal endophyte Phoma sp. The structures of the new compounds were elucidated by detailed spectroscopic analysis, and the relative configuration of 1 was confirmed by ROESY experiments. Preliminary studies indicated that compounds 2–5 possess good antibacterial, antifungal, and algicidal properties. Similarly, compound 1 showed antifungal and algicidal, and compound 6 antibacterial and algicidal properties.


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