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Two New Cyclic Pentapeptides from the Marine-Derived Fungus Aspergillus versicolor

✍ Scribed by Li-Na Zhou; Hu-Quan Gao; Sheng-Xin Cai; Tian-Jiao Zhu; Qian-Qun Gu; De-Hai Li

Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
158 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis

Two new cyclic pentapeptides, named versicotides A (1) and B (2), were obtained from a marinederived fungus strain ZLN-60, identified as Aspergillus versicolor. Their structures were established on the basis of chemical and spectroscopic evidence. Versicotides are new cyclic pentapeptides which contain an l-alanine residue, two anthranilic acid (ΒΌ 2-aminobenzoic acid) residues, and two N-methyl-lalanine residues. Antitumor activities were evaluated by the SRB and MTT methods.

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