Two New Citrinin Dimers from a Volcano Ash-Derived Fungus, Penicillium citrinum HGY1-5
✍ Scribed by Hong-Chun Liu; Lin Du; Tian-Jiao Zhu; De-Hai Li; Mei-Yu Geng; Qian-Qun Gu
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- German
- Weight
- 214 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Two new citrinin dimers, penidicitrinin A ((2__R__,3__S__,5a__S__,9__R__,10__S__,12a__R__,12b__R__)‐2,3,5a,6,9,10,12a,12b‐octahydro‐7,12a‐dihydroxy‐12b‐methoxy‐2,3,4,9,10,11‐hexamethyl‐5__H__‐difuro[2,3‐b : 2′,3′‐h]xanthen‐5‐one; 1) and penidicitrinin B ((1__S__,3__R__,4__S__)‐1‐{2,6‐dihydroxy‐4‐[(1__S__,2__R__)‐2‐hydroxy‐1‐methylpropyl]‐3‐methylphenyl}‐3,4‐dihydro‐3,4,5‐trimethyl‐1__H__‐2‐benzopyran‐6,8‐diol; 2), together with three known citrinin monomers were isolated from a volcano ash‐derived fungus, Penicillium citrinum HGY1‐5. Their structures were established by spectroscopic methods, and they showed no cytotoxicity against two tumor cell lines.