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Two new 9,11-secosterols from the marine sponge Spongia officinalis. Synthesis of 9,11-seco-3β,6α,11-trihydroxy-5α-cholest-7-en-9-one

✍ Scribed by Anna Migliuolo; Vincenzo Piccialli; Donato Sica


Book ID
116065676
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
432 KB
Volume
57
Category
Article
ISSN
0039-128X

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Partial synthesis of a marine secosterol
✍ Alexander Kuhl; Wolfgang Kreiser 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 207 KB

The conversion ofdesoxycholic acid (2) into the title compound 14 by 13 respectively 17 steps is described herein, including stereoselective construction of C-3 and C-6 hydroxy moieties and introduction of a A 9"lj double bond by dehydrogenation. 14 is believed to serve as a putative precursor for t