✦ LIBER ✦
Two New 7-Dehydrobrefeldin A Acids from Cylindrocarpon obtusisporum, an Endophytic Fungus of Trewia nudiflora
✍ Scribed by Bu-Zhu Yu; Na Zhu; Zhi-Zhi Du
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- German
- Weight
- 156 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Two new 7‐dehydrobrefeldin A acids, (2__E__,4__R__*)‐4‐hydroxy‐4‐{(1__R__*,2__S__*)‐4‐oxo‐2‐[(1__E__)‐6‐oxohept‐1‐en‐1‐yl]cyclopentyl}but‐2‐enoic acid (3) and (2__E__,4__R__*)‐4‐hydroxy‐4‐{(1__R__*,2__S__*)‐2‐[(1__E__,6__S__*)‐6‐hydroxyhept‐1‐en‐1‐yl]‐4‐oxocyclopentyl}but‐2‐enoic acid (4), were isolated from the endophytic fungal strain Cylindrocarpon obtusisporum (Cooke & Harkness) Wollenw. of Trewia nudiflora, together with two known compounds, 7‐dehydrobrefeldin A (2) and brefeldin A (1). Their structures were determined on the basis of extensive 1D‐ and 2D‐NMR‐spectral analysis.