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Two New 23-Membered Macrolactones from a Terrestrial Bacterium, Streptomyces sp. IMBJ01

✍ Scribed by Jing-Yan Gu; Wen-Jun Han; Fang-Fang Qi; Jing Li; Shi-Wei Sun; Tian-Jiao Zhu; Wen-Jun Mao; Qian-Qun Gu; De-Hai Li


Publisher
John Wiley and Sons
Year
2011
Tongue
German
Weight
168 KB
Volume
94
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Two new unusual 23‐membered macrolactones, named griseoviridins B (1) and C (2), along with the known analogue griseoviridin (3) were isolated from the culture of Streptomyces sp. IMBJ01, a terrestrial bacterium isolated from Wolong, Sichuan Province, China. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic data and their absolute configurations were determined by comparison of their CD spectra with those of compound 3.