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Two-Fold Amino Acid-Based Chiral Aminophosphine—Oxazolines and Use in Asymmetric Allylic Alkylation.

✍ Scribed by Catherine Blanc; Jerome Hannedouche; Francine Agbossou-Niedercorn


Book ID
101950619
Publisher
John Wiley and Sons
Year
2003
Weight
132 KB
Volume
34
Category
Article
ISSN
0931-7597

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Two-fold amino acid-based chiral aminoph
✍ Catherine Blanc; Jérôme Hannedouche; Francine Agbossou-Niedercorn 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 204 KB

Chiral aminophosphine-oxazoline ligands derived from two different amino acids (tetrahydroisoquinoline carboxylic acid and proline) have been synthesized and examined as chiral auxiliaries in asymmetric allylic alkylation of three substrates. Stereoisomers 1a and 2a are providing the highest enantio