Preparative and analytical separation of
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Dr. Gottfried Blaschke; Georg Hempel; Walter E. MΓΌller
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Article
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1993
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John Wiley and Sons
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English
β 276 KB
We report the preparative separation of rac-zopiclone using malic acid as the resolving agent. Furthermore, two different methods for the analytical determination of zopiclone enantiomers by HPLC on chiral stationary phases are described. The benzodiazepine receptor binding of the isolated enantiome