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Two Distinct Cytokines Released from a Human Aminoacyl-tRNA Synthetase

✍ Scribed by Wakasugi, K.


Book ID
121160840
Publisher
American Association for the Advancement of Science
Year
1999
Tongue
English
Weight
745 KB
Volume
284
Category
Article
ISSN
0036-8075

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## Abstract Aminoacyl‐tRNA synthetases catalyze the first step of protein synthesis by aminoacylation of tRNAs. Remarkably, biological fragments of two human enzymes – tyrosyl‐tRNA synthetase (TyrRS) and tryptophanyl‐tRNA synthetase – are active cytokines produced by proteolysis or alternative spli