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Two-dimensional gel analysis of secreted proteins induced by interleukin-1β in rat astrocytes

✍ Scribed by Julia W Chang; Donald A Young; Paul D Coleman; M.Kerry O'Banion


Book ID
117409672
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
350 KB
Volume
39
Category
Article
ISSN
0197-0186

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Interleukin-1 beta (IL-1␤) has been proposed as a mediator of several forms of brain damage, including that induced by excitotoxins. In vitro studies suggest that glial cells are the effector cells of IL-1␤-mediated neurodegeneration. We have investigated the expression of IL-1␤ protein by glial cel