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Two different schedules of irinotecan (CPT-11) in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil and leucovorin combination. A randomized study

✍ Scribed by N. Tsavaris; N. Ziras; C. Kosmas; T. Giannakakis; P. Gouveris; M. Vadiaka; A. Dimitrakopoulos; D. Karadima; S. Rokana; E. Papalambros; G. Papastratis; H. Margaris; H. Tsipras; A. Polyzos


Publisher
Springer
Year
2003
Tongue
English
Weight
213 KB
Volume
52
Category
Article
ISSN
0344-5704

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Prolonged gemcitabine infusion in advanc
✍ Anna Ceribelli; Cesare Gridelli; Filippo De Marinis; Alessandra Fabi; Teresa Gam πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 86 KB πŸ‘ 2 views

## Abstract ## BACKGROUND Preclinical and clinical evidence suggests that a fixed infusion rate of 10 mg/m^2^ per minute may be more effective than the standard 30‐minute infusion of gemcitabine. To investigate the activity and toxicity of the cisplatin plus gemcitabine combination with gemcitabin