✦ LIBER ✦
Two decades of new concepts in nitric oxide signaling: From the discovery of a gas messenger to the mediation of nonenzymatic posttranslational modifications
✍ Scribed by Antonio Martínez-Ruiz; Santiago Lamas
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 177 KB
- Volume
- 61
- Category
- Article
- ISSN
- 1521-6543
- DOI
- 10.1002/iub.144
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✦ Synopsis
Abstract
For the past 20 years, nitric oxide (NO) has established itself as a gaseous free radical with crucial and unpredicted roles in a wide spectrum of biological functions and organisms. We present here a case whereby NO‐mediated signaling can be broadly classified into classical (cGMP‐mediated) and nonclassical, the latter mainly alluding to posttranslational modifications related to NO and its interaction with reactive groups in proteins. © 2008 IUBMB IUBMB Life, 61(2): 91–98, 2009