✦ LIBER ✦
Two complementation groups of Fanconi's anemia differ in their phenotypic response to a DNA-crosslinking treatment
✍ Scribed by E. Moustacchi; D. Papadopoulo; C. Diatloff-Zito; M. Buchwald
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 347 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
The two genetic complementation groups reported for Fanconi's anemia (FA) correspond to two phenotypic classes as characterized by measurements of the rate of DNA semiconservative synthesis after 8-methoxypsoralen photoaddition. This test allows a rapid genetic classification of FA patients which appears to be a prerequisite for investigations of the biochemical defect(s) in FA.