## Abstract Metastasis is the primary cause of mortality in Neuroblastoma (NB) patients, but the metastatic process in NB is poorly understood. Metastsis is a multistep process that requires the coordinated action of many genes. The identification of genes that promote or suppress tumor metastasis
Two cases of localized neuroblastoma with multiple segmental chromosomal alterations and metastatic progression
β Scribed by Andres Morales La Madrid; Melanie Beglin Nall; Karen Ouyang; Agata Minor; Gordana Raca; Paul Kent; Ira Miller; Gudrun Schleiermacher; Isabelle Janoueix-Lerosey; Susan L. Cohn
- Book ID
- 115560700
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 172 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1545-5009
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## Abstract We have constructed a 1.4βMb P1 artificial chromosome/bacterial artificial chromosome (PAC/BAC) contig spanning the 17q breakpoint of a constitutional translocation t(1;17)(p36.2;q11.2) in a patient with neuroblastoma. Three 17q breakpointβoverlapping cosmids were identified and sequenc