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Two Cases of Acute Myeloblastic Leukemia Evolving from Aplastic Anemia

✍ Scribed by Akihiko Taguchi; Takayuki Tominaga; Yoshitaka Nakamori; Mutsuko Miyazaki; Kenji Shinohara

Publisher: Carden Jennings Publishing
Year: 2003
Tongue: English
Weight: 379 KB
Volume: 77
Category: Article
ISSN: 0925-5710
DOI: 10.1007/bf02986615

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## Abstract Double minutes (dmin) are small, paired chromatin bodies that lack a centromere and represent a form of extrachromosomal gene amplification. Although they have been found in a variety of solid tumors, their presence in hematological malignancies, especially acute myeloid leukemia (AML),