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Two CA/GT repeat polymorphisms in intron 27 of the human neurofibromatosis type 1 (NF1) gene

✍ Scribed by Conxi Lázaro; Antonia Gaona; Xavier Estivill


Publisher
Springer
Year
1994
Tongue
English
Weight
297 KB
Volume
93
Category
Article
ISSN
0340-6717

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We studied 20 unrelated NF1 patients by Southern blots with seven cDNA probes and loss of heterozygosity (LOH) analysis with four intragenic microsatellites (IVS26-2.3, IVS27AC28.4, IVS27AC33.1, and IVS38GT53.0). Four novel large deletions (178, 184, 236, and 237) have been identified and characteri