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Two antiestrogens affect differently chromatin remodeling of trefoil factor 1 (pS2) gene and the fate of estrogen receptor in MCF7 cells

✍ Scribed by Claire Giamarchi; Catherine Chailleux; Mathide Calligé; Philippe Rochaix; Didier Trouche; Hélène Richard-Foy

Book ID: 114147622
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 465 KB
Volume: 1578
Category: Article
ISSN: 0167-4781
DOI: 10.1016/s0167-4781(02)00480-3

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## Abstract To further explore the role of Sp1 and Sp3 in the estrogen regulated TFF1 gene transcription, chromatin immunoprecipitation (ChIP) assay was used to determine the association of estrogen receptor α (ERα), Sp1 and Sp3 with the endogenous trefoil factor 1 (TFF1) gene promoter in MCF‐7 bre