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Twisted gastrulation is a conserved extracellular BMP antagonist

✍ Scribed by Ross, Jeffrey J.; Shimmi, Osamu; Vilmos, Peter; Petryk, Anna; Kim, Hyon; Gaudenz, Karin; Hermanson, Spencer; Ekker, Stephen C.; O'Connor, Michael B.; Marsh, J. Lawrence

Book ID
109774079
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
294 KB
Volume
410
Category
Article
ISSN
0028-0836

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## Abstract Bone morphogenetic proteins (BMPs) have been shown to regulate both osteoblasts and osteoclasts. We previously reported that BMP2 could directly enhance RANKL‐mediated osteoclast differentiation by increasing the size and number of osteoclasts. Similarly, genetic deletion of the BMP ant