Twice-a-day radiotherapy for T3 squamous cell carcinoma of the glottic larynx

✍ Scribed by Dr. James T. Parsons; William M. Mendenhall; Anthony A. Mancuso; Nicholas J. Cassisi; Scott P. Stringer; Rodney R. Million

• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: English
• Weight: 552 KB
• Volume: 11
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.2880110204

✦ Synopsis

Between March 1978 and April 1986, 21 previously untreated patients with T3 squarnous cell carcinoma of the true vocal cord received radical courses of twice-a-day radiotherapy (1 20 cGy twice daily) to total doses of 7,440-7,680 cGy. The rate of local control at the primary site was 67% after radiotherapy. The ultimate control rate after salvage surgery was 83%. Five-year absolute and cause-specific survival rates were 59% and 81%, respectively. It is concluded that radiotherapy is a rational approach for many patients with T3 glottic cancer HEAD &

NECK, 11:123-128, 1989

Since March 1978, twice-a-day radiotherapy with curative intent has been offered to some patients with T3 vocal cord cancer as a means of voice preservation at our institution. During the study period encompassed by the present publication (March 1978-April l986), there was no uniform policy for selecting treatment by radiotherapy or surgery. In the early years of the study period, the tendency was to recommend surgery for most patients and to use radiotherapy for patients who refused or had medical contraindications to surgery or whose livelihoods From the Departments of Radiation Oncology and Radiology and the Di-