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Twelve-Nucleotide Repeat Polymorphism of D4 Dopamine Receptor Gene in Chinese Familial Schizophrenic Patients

โœ Scribed by Chen-Jee Hong; Hsien-Jane Chiu; Yea-Shin Chang; Cho-Boon Sim


Book ID
118511101
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
30 KB
Volume
43
Category
Article
ISSN
0006-3223

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48โ€bp repeat, which range from two to ten copies in t