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TWEAK can induce cell death via endogenous TNF and TNF receptor 1

✍ Scribed by Pascal Schneider; Ralph Schwenzer; Elvira Haas; Frank Mühlenbeck; Gisela Schubert; Peter Scheurich; Jürg Tschopp; Harald Wajant

Book ID
101310923
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
186 KB
Volume
29
Category
Article
ISSN
0014-2980

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## Abstract TNF is a pleiotropic cytokine with intriguing biphasic pro‐inflammatory and anti‐inflammatory effects. Our previous studies demonstrated that TNF up‐regulated FoxP3 expression and activated and expanded CD4^+^FoxP3^+^ regulatory T cells (Tregs) via TNFR2. Furthermore, TNFR2‐expressing T