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Tutorial in Biostatistics A review of tests for detecting a monotone dose–response relationship with ordinal response data

✍ Scribed by Christy Chuang-Stein; Alan Agresti


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
344 KB
Volume
16
Category
Article
ISSN
0277-6715

No coin nor oath required. For personal study only.

✦ Synopsis


This tutorial reviews methods for testing independence between discrete levels of a dose and an ordered categorical response variable. The tests are designed to be powerful for cases in which the response improves monotonically as dosage level increases. First, we show how to apply some standard tests for doublyordered contingency tables. Then, we show how to construct tests as part of a model-building strategy. Other topics discussed include generalizations to stratified data, small-sample methods, and sample size and power considerations.