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Turning off signal transducer and activator of transcription (STAT): The negative regulation of STAT signaling

Book ID: 119274651
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 35 KB
Volume: 114
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2004.07.009

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## Abstract Signal transducer and activator of transcription 3 (Stat3) is one of a family of cytoplasmic proteins that participate in normal cellular responses to cytokines and growth factors as transcription factors. Stat3 modulates various physiological functions including cell survival, cell‐cyc