Turbulent breakage of protein precipitates in mechanically stirred bioreactors

✍ Scribed by P. Ayazi Shamlou; S. Stavrinides; N. Titchener-Hooker; M. Hoare

• Book ID: 104744564
• Publisher: Springer
• Year: 1996
• Tongue: English
• Weight: 812 KB
• Volume: 14
• Category: Article
• ISSN: 1615-7605
• DOI: 10.1007/bf00369919

✦ Synopsis

Experimental data relating to the breakage of isoelectric Soya protein precipitates in a mechanically agitated bioreactor are provided and examined in the light of a proposed mechanistic model which relates the size of the maximum attainable aggregate diameter to the energy dissipation rate in the vessel. The analysis suggests that protein precipitation results in the formation of scale-invariant fractal aggregates with a dimensionality of 2.2. Comparing the fractal dimensionality of the protein precipitates with reported values based on computer simulation studies suggests that the aggregates undergo considerable restructuring during agitation.