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Tuning of CD40–CD154 Interactions in Human B-Lymphocyte Activation: A Broad Array of In Vitro Models for a Complex In Vivo Situation

✍ Scribed by Sonia Néron; Philippe J. Nadeau; André Darveau; Jean-François Leblanc

Book ID
105751195
Publisher
Springer
Year
2011
Tongue
English
Weight
425 KB
Volume
59
Category
Article
ISSN
0004-069X

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Activated human T cells express a ligand
Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes
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## Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes To identify the ligand for the B cell-associated antigen CD40, we constructed a chimeric immunoglobulin molecule where the extracellular porti