Tumour Necrosis Factor Alpha Stimulates the Production of Monocyte Chemoattractants by Extravillous Trophoblast Cells via Differential Activation of MAPK Pathways

Effects of retinoids on the production o

Effects of retinoids on the production of tumour necrosis factor-alpha and nitric oxide by lipopolysaccharide-stimulated rat Kupffer cells in vitro: evidence for participation of retinoid X receptor signalling pathway

✍ Kenta Motomura; Hironori Sakai; Hidehiko Isobe; Hajime Nawata 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 243 KB 👁 3 views

Kupffer cells play important roles in the development of liver injury by producing cytokines and free radicals. In consequence inhibition of these inflammatory mediators will be one of the targets for treating liver diseases. Retinoids modulate a wide variety of functions of monocytes/macrophages. C