Tumour-derived TGF-β1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

Expression of proangiogenic chemokine Gr

Expression of proangiogenic chemokine Gro 1 in low and high metastatic variants of Pam murine squamous cell carcinoma is differentially regulated by IL-1α, EGF and TGF-β1 through NF-κB dependent and independent mechanisms

✍ Elena Loukinova; Zhong Chen; Carter Van Waes; Gang Dong 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 186 KB

## We previously reported that chemokine Growth Regu lated Oncogene 1 (Gro 1) is over-expressed in murine squamous cell carcinoma (SCC) with metastatic tumor progression. The enhanced expression of Gro-1 gene by SCC is regulated by activation of nuclear factor-B (NF-B), leading to accelerated tumor