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Tumour class prediction and discovery by microarray-based DNA methylation analysis

✍ Scribed by S. Maier; P. Adorjan; J. Distler; E. Lipscher; J. Mueller; C. Pelet; C. Scholz; K. Berlin; C. Piepenbrock; A. Olek

Book ID
117657940
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
166 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Abstract Gene silencing via promoter CpG island hypermethylation offers tumor cells growth advantages. This epigenetic event is pharmacologically reversible, and uncovering a unique set of methylation‐silenced genes in tumor cells can bring a new avenue to cancer treatment. However, high‐through